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Invitrogen™ Phospho-PPP1R8 (Ser199) Polyclonal Antibody
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Product Code. 16621535
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Quantity:
100 μL
Unit Size:
100µL
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16621535 100 μL 100µL
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Product Code. 16621535 Supplier Invitrogen™ Supplier No. PA5105085

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PPP1R8/ARD1 only when phosphorylated at Ser199.

This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PPP1R8 (Ser199)
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene PPP1R8
Gene Accession No. Q12972, Q8R3G1
Gene Alias 6330548N22Rik; activator of RNA decay; ARD1; ARD-1; AU044684; LOC100722083; NIPP1; NIPP-1; NIPP-1, nuclear inhibitor of protein phosphatase-1; Nuclear inhibitor of protein phosphatase 1; nuclear inhibitor of protein phosphatase-1 alpha; nuclear inhibitor of protein phosphatase-1 beta; nuclear subunit of PP-1; Ppp1r8; PRO2047; protein phosphatase 1 regulatory inhibitor subunit 8; protein phosphatase 1 regulatory subunit 8; protein phosphatase 1, regulatory (inhibitor) subunit 8; protein phosphatase 1, regulatory inhibitor subunit 8; protein phosphatase 1, regulatory subunit 8; RNase E
Gene Symbols PPP1R8
Host Species Rabbit
Immunogen A synthesized peptide derived from human PPP1R8(Accession Q12972), corresponding to amino acid residues around phosphorylated Ser199.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100336, 313030, 5511
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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