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Invitrogen™ Phospho-PTRF (Tyr156) Polyclonal Antibody
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Product Code. 16643825
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Quantity:
100 μL
Unit Size:
100µL
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16643825 100 μL 100µL
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Product Code. 16643825 Supplier Invitrogen™ Supplier No. PA599575

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of PTRF only when phosphorylated at Tyr156.

The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-PTRF (Tyr156)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CAVIN1
Gene Accession No. O54724, P85125, Q6NZI2
Gene Alias 2310075E07Rik; AW546441; caveolae associated protein 1; caveolae-associated protein 1; CAVIN; CAVIN1; cavin-1; Cav-p60; CGL4; FKSG13; FLJ90031; Polymerase I and transcript release factor; PTRF; ptrf {ECO:0000312; RGD:1307685}; RNA polymerase I and transcript release factor; TTF-I interacting peptide 12
Gene Symbols CAVIN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human CAVIN1(Accession Q6NZI2), corresponding to amino acid residues around phosphorylated Tyr156.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 19285, 284119, 287710
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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