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Invitrogen™ Phospho-RAD17 (Ser645) Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA578145
This item is not returnable.
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Description
Positive Control: HeLa Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
Specifications
| Phospho-RAD17 (Ser645) | |
| Polyclonal | |
| Unconjugated | |
| Rad17 | |
| CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5884 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1.44 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| O75943 | |
| Rad17 | |
| Carrier-protein conjugated synthetic peptide surrounding phospho Ser645 of human Rad17. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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