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Invitrogen™ Phospho-RAD17 (Ser656) Polyclonal Antibody
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Product Code. 16352645
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16352645 100 μL 100µL
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Product Code. 16352645 Supplier Invitrogen™ Supplier No. PA585713

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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Positive Control: 293T (100 uM etoposide treatment for 2 hrs). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Rad17 is essential for sustained cell growth, maintenance of chromosomal stability, and ATR-dependent checkpoint activation upon DNA damage. It has a weak ATPase activity required for binding to chromatin. Rad17 also participates in the recruitment of the RAD1-RAD9-HUS1 complex and RHNO1 onto chromatin, and in CHEK1 activation. May also serve as a sensor of DNA replication progression, and may be involved in homologous recombination.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-RAD17 (Ser656)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 2.25 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene Rad17
Gene Accession No. O75943
Gene Alias CCYC; cell cycle checkpoint protein (RAD17); cell cycle checkpoint protein RAD17; DNA damage checkpoint control protein RAD17; DNA repair exonuclease RAD17; FLJ41520; hRad17; MmRad24; R24L; RAD1 homolog; RAD17; RAD17 (Ser647); RAD17 checkpoint clamp loader component; RAD17 homolog; RAD17 homolog (S. pombe); Rad17 like protein; Rad17-like protein; Rad17p; RAD17SP; RAD24; RF-C activator 1 homolog; RF-C/activator 1 homolog; YOR368W
Gene Symbols Rad17
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide surrounding phospho Ser656 of human Rad17. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5884
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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