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Invitrogen™ Phospho-RASGRF1 (Ser927) Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5105157
This item is not returnable.
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Description
Antibody detects endogenous levels of Ras-GRF1 only when phosphorylated at Ser927.
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
Specifications
| Phospho-RASGRF1 (Ser927) | |
| Polyclonal | |
| Unconjugated | |
| RASGRF1 | |
| AI844718; ASPP1; Cdc25; CDC25L; CDC25Mm; Gnrp; GRF1; GRF55; Grfbeta; guanine nucleotide exchange factor; guanine nucleotide-releasing factor 1; guanine nucleotide-releasing factor, 55 kD; guanine nucleotide-releasing protein; H-GRF55; KIAA0771; P140 Ras-GRF; p190; P190-A; p190RhoGEF; PP13187; PPP1R13B; Ras guanine release factor beta; Ras protein specific guanine nucleotide releasing factor 1; RAS protein-specific guanine nucleotide-releasing factor 1; Rasgrf1; ras-GRF1; Ras-specific guanine nucleotide-releasing factor 1; Ras-specific guanine nucleotide-releasing factor, CDC25 homolog; ras-specific nucleotide exchange factor CDC25 | |
| Rabbit | |
| sequential chromatography | |
| RUO | |
| 192213, 19417, 5923 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P27671, P28818, Q13972 | |
| RASGRF1 | |
| A synthesized peptide derived from human RASGRF1(Accession Q13972), corresponding to amino acid residues around phosphorylated Ser927. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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