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Invitrogen™ Phospho-RNA pol II CTD (Ser2, Ser5) Recombinant Rabbit Monoclonal Antibody (10W0C8)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA551533

Product Code. 18035511

  • € 435.00 / 100µL

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Description

Description

Phospho-RNA pol II CTD (Ser2, Ser5) Recombinant Monoclonal Antibody for Western Blot, IP, ChIP, ELISA, C&R

RNA polymerase II is the enzyme responsible for the synthesis of mRNA and many non-coding RNAs. POLR2A encodes RNA polymerase II subunit B1 (RPB1), the largest subunit of RNA polymerase II. The C-terminal domain (CTD) of RPB1 contains tandem heptapeptide repeats with the consensus sequence YSPTSPS. Phosphorylation and other modifications within this sequence influence the recruitment of factors that regulate the transcription cycle. Recruitment of RNA processing factors to the elongation complex is coordinated by the phosphorylation of Serine-2 and Serine-5 residues within the CTD.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-RNA pol II CTD (Ser2, Ser5)
Recombinant Monoclonal
0.09 mg/mL
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3
P24928
POLR2A
A phospho specific peptide corresponding to residues surrounding S2/S5 of human POLR2A.
100 μL
Primary
Human, Rat
Antibody
Liquid
ChIP Assay, ELISA, Immunoprecipitation, Western Blot, CUT&RUN
10W0C8
Unconjugated
POLR2A
220kDa; AW321876; DNA polymerase alpha 1 catalytic subunit; DNA polymerase alpha 1, 180 kDa; DNA polymerase alpha 1, catalytic subunit; DNA polymerase alpha catalytic subunit; DNA polymerase alpha catalytic subunit p180; DNA polymerase alpha p180 subunit; DNA polymerase alpha subunit I; DNA polymerase epsilon catalytic subunit; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; DUN2; EC 2.7.7.6; G7a/Bat6Hom; hRPB220; hsRPB1; I79_002751; I79_016081; MGC75453; N0825; NSX; p180; Pol II S2p; POL2; Pola; Pola1; POLR2; POLR2A; POLRA; polymerase (DNA directed), alpha 1; polymerase (DNA directed), alpha 1, catalytic subunit; polymerase (DNA) alpha 1, catalytic subunit; polymerase (DNA-directed), alpha (70kD); Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; polymerase, alpha 1; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II carboxy-terminal domain; RNA polymerase II C-terminal domain; RNA polymerase II largest subunit; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8; YNL262W
Rabbit
Affinity Chromatography
RUO
363633, 5430
-20°C, Avoid Freeze/Thaw Cycles
Liquid
IgG
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