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Invitrogen™ Phospho-SF1 (Ser82) Polyclonal Antibody

Product Code. 15536971
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Quantity:
100 μL
Unit Size:
100µL
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15536971 100 μL 100µL
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Product Code. 15536971 Supplier Invitrogen™ Supplier No. PA540282

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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with mouse and monkey based on sequence homology.

Splicing factor 1 is a nuclear pre-mRNA splicing factor. The protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-SF1 (Ser82)
Applications ELISA, Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene SF1
Gene Accession No. Q15637, Q64213
Gene Alias BBP; D11S636; M ZFM1; Mammalian branch point-binding protein; MBBP; MZFM; SF; SF1; Splicing factor 1; transcription factor ZFM1; WBP4; wu:fc09f06; ZCCHC25; ZFM1; Zfp162; Zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162
Gene Symbols SF1
Host Species Rabbit
Immunogen Synthesized peptide derived from human Splicing factor 1 around the phosphorylation site of S82.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22668, 7536
Target Species Human, Mouse, Monkey
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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