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Invitrogen™ Phospho-Tensin 1 (Tyr483) Polyclonal Antibody

Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Tensin is involved in the maintenance of cellular structure by anchoring Actin filaments at the focal adhesion via F-Actin binding and capping activities. However, tensin also contains a Src homology 2 (SH2) domain and has the ability to be phosphorylated. Tensin is phosphorylated on tyrosine, serine, and threonine residues, suggesting that it might participate in signal transduction cascades. These diverse characteristics in a single molecule indicate that tensin may be an important link between the cytoskeleton and signal transduction pathways.
Specifications
Specifications
| Antigen | Phospho-Tensin 1 (Tyr483) |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | TNS1 |
| Gene Accession No. | Q9HBL0 |
| Gene Alias | 1110018I21Rik; 1200014E20Rik; AI648117; DKFZp586K0617; E030018G17Rik; E030037J05Rik; matrix-remodelling associated 6; Matrix-remodelling-associated protein 6; MGC88584; MST091; MST122; MST127; MSTP091; MSTP122; MSTP127; MXRA6; PPP1R155; protein phosphatase 1, regulatory subunit 155; tensin 1; tensin-1; TNS; TNS1 |
| Gene Symbols | TNS1 |
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