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Invitrogen™ Phospho-TNK1 (Tyr277) Polyclonal Antibody
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Product Code. 16601125
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Quantity:
100 μL
Unit Size:
100µL
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16601125 100 μL 100µL
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Product Code. 16601125 Supplier Invitrogen™ Supplier No. PA5104671

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of TNK1 only when phosphorylated at Tyr277.

TNK1 tyrosine kinase, non-receptor 1 belongs to the tyrosine protein kinase family and as such is an important regulator of intracellular signal transduction pathways mediating cellular proliferation, survival, and development. TNK1 is highly expressed in fetal tissues and at lower levels in a few adult tissues. TNK1 may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. TNK1 plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-TNK1 (Tyr277)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TNK1
Gene Accession No. Q13470, Q99ML2
Gene Alias CD38 negative kinase 1; Kinase of embryonic stem cells; Kos1; MGC46193; non-receptor tyrosine kinase; non-receptor tyrosine-protein kinase TNK1; TNK1; Tnk1a; Tnk1b; tyrosine kinase non receptor 1; tyrosine kinase, non-receptor 1; tyrosine kinase, non-receptor, 1
Gene Symbols TNK1
Host Species Rabbit
Immunogen A synthesized peptide derived from human TNK1(Accession Q13470), corresponding to amino acid residues around phosphorylated Tyr277.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 303247, 83813, 8711
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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