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Phospho-VEGF Receptor 2 (Tyr1054) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Brand: Invitrogen PA538540
This item is not returnable.
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Description
Three cell membrane receptor tyrosine kinases, Flt (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulinlike sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
Specifications
| Phospho-VEGF Receptor 2 (Tyr1054) | |
| Polyclonal | |
| Unconjugated | |
| KDR | |
| Vascular endothelial growth factor receptor 2, VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1, CD309, KDR, FLK1, VEGFR2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 16542, 25589, 3791 | |
| -20°C | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 1 mg/mL | |
| Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P35968, P35918, O08775 | |
| KDR | |
| A synthetic phosphopeptide derived from human VEGFR2 around the phosphorylation site of Tyr1054 (D-I-YP-K-D) | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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