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Thermo Scientific™ Pierce™ Cypridina Luciferase Glow Assay Kit

Product Code. 12201622 Shop All Thermo Scientific Products
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Quantity:
100 Reaction Kit
1000 Reaction Kit
Unit Size:
Each
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Product Code. 12201622

Brand: Thermo Scientific™ 16170

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This item is not returnable. View return policy

Obtain bright and stable bioluminescence signal (half-life greater than 1 hour) in the presence of Cypridina luciferase reporters.

The Thermo Scientific™ Pierce Cypridina Luciferase Glow Assay Kit provides an extremely bright and stable bioluminescence signal (half-life greater than 1 hour) in the presence of Cypridina luciferase reporters.

This Pierce Luciferase Glow Assay Kit contains reagents for measuring Cypridina luciferase activity in mammalian cell culture media and lysates. When used with Thermo Scientific Cypridina Luc Vectors, the kit provides an extremely sensitive bioluminescent reporter assay system for secreted or intracellular detection of luciferase activity. The light output generated by the luciferase reaction can be correlated to the amount of luciferase protein produced, which in turn is proportional to the activity of the promoter driving the luciferase expression. The kit can be used to detect the activity of any Cypridina luciferases or derivatives that use Vargulin as a substrate.

Highlights:

  • Sensitive – highly sensitive detection of Cypridina luciferase activity

  • Secreted luciferase – allows real-time assays and kinetic studies without destroying cells

  • Stable – reagents provide increased signal stability compared to flash assays

  • Simple – does not require a luminometer with injectors

  • Compatible – assay reagents compatible with other Cypridina or Vargula luciferases

  • Automation-friendly – amenable to high throughput assays

  • Convenient – contains a universal cell lysis buffer and optimized glow assay reagent

  • Safe – allows one to perform non-radioactive assays

Includes:

Cell lysis buffer, reaction buffer and substrate

Requires:

Cypridina luciferase and luminometer or other instrument capable of monitoring luminescence, such as Thermo Scientific Luminoskan Ascent and Varioskan Flash Microplate Readers

Recommended for:

Promoter studies for analyzing cis- regulatory elements and trans-acting factors; Drug screening; siRNA and miRNA screening; Multiplexed assays to study off-target effects; Secretory pathway / protein localization reporter assays; Signal transduction pathway analysis; RNA splicing studies

TRUSTED_SUSTAINABILITY

Spezifikation

Type Assay Kit
Target Luciferase, Cypridina Luciferase
Quantity 100 Reaction Kit
Content And Storage • Cypridina Glow Assay Buffer, 5 mL, store at 4°C
• Vargulin (1X), 5 μL, store at -20°C
• 2X Cell Lysis Buffer, 6 mL, store at room temperature

Upon receipt store kit at -20°C or store individual components as indicated above.
Assay Reporter Enzyme, Luciferase Reporter Assay
Compatible Cells Mammalian Cells
Detection Method Bioluminescence
For Use With (Equipment) Luminometer (Microplate)
Format 384-well plate, 96-well plate
Label Type Enzyme Labeled
Substrate Properties Chemical Substrate
Technique Enhanced Chemiluminescence
Substrate Type Luciferase Substrate
Product Line Pierce
Substrate Vargulin (Cypridina Luciferin)
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Produktidentifikator
  • Pierce Cypridina Luciferase Glow Assay Kit
Signalwort
  • Danger
Gefahrenkategorie
  • Acute toxicity Category 3
  • Serious eye damage/eye irritation Category 1
  • Flammable liquid Category 2
  • Skin corrosion/irritation Category 1 A
  • Specific target organ toxicity after single exposure Category 1
Gefahrenhinweis
  • H225-Highly flammable liquid and vapour.
  • H301-Toxic if swallowed.
  • H311-Toxic in contact with skin.
  • H314-Causes severe skin burns and eye damage.
  • H331-Toxic if inhaled.
  • H370-Causes damage to organs.
Sicherheitshinweis
  • P210-Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P233-Keep container tightly closed.
  • P241-Use explosion-proof electrical/ventilating/lighting/ equipment.
  • P243-Take precautionary measures against static discharge.
  • P260-Do not breathe dust/fume/gas/mist/vapours/spray.
  • P264-Wash hands thoroughly after handling.
  • P270-Do not eat, drink or smoke when using this product.
  • P271-Use only outdoors or in a well-ventilated area.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P310-IF SWALLOWED: Immediately call a POISON CENTER/doctor /
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P308+P313-IF exposed or concerned: Get medical advice/attention.
  • P363-Wash contaminated clothing before reuse.
  • P403+P235-Store in a well-ventilated place. Keep cool.
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
Ergänzende Informationen
  • MIXTURE LIST-Contains : methanol

For Research Use Only. Not for use in diagnostic procedures.

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