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PIM2 Mouse anti-Human, Clone: OTI8B4, lyophilized, TrueMAB™
Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
Specifications
Specifications
| Antigen | PIM2 |
| Applications | Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Monoclonal |
| Clone | OTI8B4 |
| Conjugate | Unconjugated |
| Formulation | PBS with 8% trehalose and no preservative; pH 7.3 |
| Gene | PIM2 |
| Gene Accession No. | Q9P1W9 |
| Gene Alias | Pim-2 proto-oncogene, serine/threonine kinase |
| Gene Symbols | PIM2 |
| Show More |
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