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Invitrogen™ PINK1 Monoclonal Antibody (3A9F8)

Product Code. 17976111
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
17976111 100 μg 100µg
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Product Code. 17976111 Supplier Invitrogen™ Supplier No. MA548780

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Description

Mouse Monoclonal Antibody

PINK1 Monoclonal Antibody for Western Blot, IHC (P), Flow, ELISA

PINK1 (PTEN-induced putative kinase 1) protects from mitochondrial dysfunction in cells by conferring different autophosphorylation activity to mitochondrial genes. The kinase domain of PINK1 appears to be critical in its protective effects. Mitochondrial proteins are critical for the regulation of cellular energy and adaptation to stress. Particularly in brain cells, mitochondrial demand is extraordinarily high, in order to accommodate aerobic and anaerobic support of high energy processes. When mitochondrial structure and/or function is disrupted in the brain, neurodegenerative diseases like Parkinson's disease are triggered.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PINK1
Applications ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Classification Monoclonal
Clone 3A9F8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene PINK1
Gene Accession No. Q9BXM7
Gene Alias 1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial
Gene Symbols PINK1
Host Species Mouse
Immunogen Purified recombinant fragment of human PINK1 (AA: 112-273) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 65018
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG2a
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