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Invitrogen™ PITX2 Polyclonal Antibody
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Product Code. 16352435
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Quantity:
100 μL
Unit Size:
100µL
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16352435 100 μL 100µL
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Product Code. 16352435 Supplier Invitrogen™ Supplier No. PA585500

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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (96%), Rat (95%), Zebrafish (87%), Japanese Medaka (86%), Xenopus laevis (88%), Pig (97%), Chicken (93%), Bovine (97%). Positive Control: PITX2-transfected 293T cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Pilx2 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. It plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this protein are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PITX2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene PITX2
Gene Accession No. Q99697
Gene Alias 9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; Arp1; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired like homeodomain transcription factor 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; paired-like homeodomain transcription factor 2; paired-like homeodomain transcription factor 2c; paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; Pitx2; Pitx-2; Pitx2c; Ptx2; Rgs; Rieg; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S a 1 glycoprotein; S a1glycoprotein; Solurshin
Gene Symbols PITX2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human PITX2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5308
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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