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PKC-IN-1, MedChemExpress

Product Code. 16489727
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Product Code. 16489727 Supplier Medchem Express Supplier No. HY16903

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Description

MedChemExpress PKC-IN-1 is a potent, ATP-competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5.3 and 10.4 nM for human PKCβ and PKCα, and IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM for PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε, respectively.

PKC-IN-1 is a potent, ATP-competitive and reversible inhibitor of conventional PKC enzymes with Kis of 5.3 and 10.4 nM for human PKCβ and PKCα, and IC50s of 2.3, 8.1, 7.6, 25.6, 57.5, 314, 808 nM for PKCα, PKCβI, PKCβII, PKCθ, PKCγ, PKC mu and PKCε, respectively.

Specifications

Chemical Name or Material PKC-IN-1
Physical Form Solid
CAS 1046787-18-1
Color Off-White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C25H37FN8O2
For Use With (Application) COVID-19-immunoregulation
Solubility Information DMSO : ≥ 25 mg/mL (49.94 mM)
SMILES O=C(N1[C@@H](C)CN(CC2CCOCC2)[C@H](C)C1)N(C3)C(C)(C)C4=C3C(NC5=NC(C)=NC=C5F)=NN4
Molecular Weight (g/mol) 500.61
Formula Weight 500.61
Percent Purity 98.79%
Grade Research
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Research purposes only

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