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Eurofins DiscoverX PKC ζ Protein, Active

Product Code. 17360294
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Quantity:
10 μg
250 μg
Unit Size:
10µg
250µg
This item is not returnable. View return policy

Product Code. 17360294

Brand: Eurofins DiscoverX 14525

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This item is not returnable. View return policy

Description

Active, N-terminal His6-tagged recombinant human PKC zeta, residues 2-end, for use in Kinase Assays.

KPCZ (Protein kinase C, zeta type, nPKC-zeta, EC 2.7.1.37) is one of the major protein kinase C (PKC) isoforms of a family of serine/threonine protein kinases. Breakdown of phosphatidylinositol leads to formation of diacylglycerol and inositol triphophate, the former acting synergistically with Ca2+ to activate PKC, resulting in translocation of the enzyme from cytosol to the membrane. Phosphorylation of proteins by PKC has been implicated as a pivotal regulatory element in signal transduction, cellular regulation, and with a high affinity to phorbol ester tumor promoters.

GenBank BC014270

Specifications

Formulation mg/mL of enzyme in 20 mM Tris/HCl pH 7.5, 0.02% Triton X-100, 5% glycerol, 1 mM EDTA, 1 mM EGTA, 0.1% 2-mercaptoethanol, 1 mM PMSF, 10 mM benzamidine. Frozen solution.
Molecular Weight (g/mol) 68.9 kDa
Quantity 10 μg
Species Human
Recombinant Recombinant
Protein Tag N-terminal 6His
Expression System Recombinant enzyme expressed in Sf21 insect cells
Protein Form Truncated
Purity or Quality Grade ≥73%
Protein PKCζ (zeta), active
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