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Invitrogen™ PLA2G4A Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5111389
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Beschreibung
Immunogen sequence: PRETEEEKEI ADFDIFDDPE SPFSTFNFQY PNQAFKRLHD LMHFNTLNNI DVIKEAMVES IEYRRQNPSR CSVSLSNVEA RRFFNKEFLS K Highest antigen sequence indentity to the following orthologs: Rat - 93%, Mouse - 93%.
This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
Spezifikation
| PLA2G4A | |
| Polyclonal | |
| Unconjugated | |
| PLA2G4A | |
| calcium-dependent phospholipid-binding protein; Cpla2; cPLA2alpha; cPLA2-alpha; cytosolic group IVA; Cytosolic phospholipase A2; group IVA; lysophospholipase; MGC126350; Phosphatidylcholine 2-acylhydrolase; Phospholipase A2; phospholipase A2 cytosolic; phospholipase A2 group IVA; phospholipase A2, group IVA (cytosolic, calcium-dependent); Pla2c; Pla2g4; PLA2G4A | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5321 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.05 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| P47712 | |
| PLA2G4A | |
| Recombinant Protein corresonding to Human PLA2G4A. Recombinant protein control fragment (Product #RP-103178). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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