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Invitrogen™ PLEKHJ1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA561857
This item is not returnable.
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Description
Immunogen sequence: FIEDPERKYH FECSSEEQCQ EWMEALRRAS YEFMRRSLIF YRNEIRKVTG KDPLEQFGIS EEARFQLSGL Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 87%.
The PLEKHJ1 (Pleckstrin Homology Domain Containing, Family J Member 1) gene encodes a protein that is involved in signal transduction and cytoskeletal organization. Located on chromosome 11, the PLEKHJ1 protein contains a pleckstrin homology (PH) domain, which facilitates its binding to phosphoinositides and the subsequent interaction with cellular membranes. This interaction is vital for various cellular processes, including the regulation of cell shape, motility, and intracellular trafficking. The precise biological functions of PLEKHJ1 are still being elucidated, but its role in these signaling pathways underscores its importance in maintaining cellular architecture and function. Alterations in PLEKHJ1 expression or mutations can have significant implications for cellular dynamics and have been linked to certain pathological conditions, including cancer.
Specifications
| PLEKHJ1 | |
| Polyclonal | |
| Unconjugated | |
| PLEKHJ1 | |
| 9530063M10Rik; Gnrpx; guanine nucleotide releasing protein x; guanine nucleotide-releasing protein x; PH domain-containing family J member 1; pleckstrin homology domain containing J1; pleckstrin homology domain containing, family J member 1; pleckstrin homology domain-containing family J member 1; Plekhj1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 55111 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.4 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q9NW61 | |
| PLEKHJ1 | |
| Recombinant protein corresponding to Human PLEKHJ1. Recombinant protein control fragment (Product #RP-98922). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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