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Invitrogen™ Plexin-A1 Monoclonal Antibody (M535)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA547679

Product Code. 17846798

  • € 548.00 / 100µL

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Description

Description

The antibody detects a 220 kDa* protein corresponding to the apparent molecular mass of Plexin-A1 on SDS-PAGE immunoblots of neonatal mouse brain, and detects a recombinant mouse Plexin A1 protein containing the extracellular region.

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Plexin-A1
Monoclonal
~1 mg/mL
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
P70206, Q9UIW2
PLXNA1
Clone M535 was generated from a Plexin-A1 synthetic peptide (coupled to carrier protein) corresponding to a region within the N-terminal half of the semaphorin domain in human Plexin-A1. This sequence is highly conserved in rat and mouse Plexin-A1, and has low homology to other Plexin family members.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG1
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
M535
Unconjugated
PLXNA1
2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; plexin-A1; PLXN1; Plxna1; RGD1560871; semaphorin receptor NOV
Mouse
Antigen affinity chromatography
RUO
18844, 362398, 5361
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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