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Invitrogen™ PLS3 Polyclonal Antibody
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Product Code. 13421847
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
13421847 100 μL 100µL
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Product Code. 13421847 Supplier Invitrogen™ Supplier No. PA527883

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, JurKat, Raji, NIH-3T3, JC, BCL-1. Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (89%), Xenopus laevis (91%), Chicken (95%), Rhesus Monkey (100%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2). Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PLS3
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7
Gene PLS3
Gene Accession No. P13797, Q99K51
Gene Alias AI115446; AL024105; BMND18; LOW QUALITY PROTEIN: plastin-3; MGC128570 protein; plastin 3; plastin 3 (T isoform); plastin 3 (T-isoform); plastin 3, T; plastin-3; PLS3; T fimbrin; T plastin; T-fimbrin; T-plastin
Gene Symbols PLS3
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human T-Plastin. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 102866, 5358
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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