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PLX647, MedChemExpress

Product Code. 16468527
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Product Code. 16468527 Supplier Medchem Express Supplier No. HY13838

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Description

MedChemExpress PLX647 is an orally active, highly specific dual FMS and KIT kinase inhibitor, with IC50s of 28 and 16 nM, respectively. PLX647 shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1 μM except FLT3 and KDR (IC50s=91 and 130 nM, respectively).

PLX647 is an orally active, highly specific dual FMS and KIT kinase inhibitor, with IC50s of 28 and 16 nM, respectively. PLX647 shows selectivity for FMS and KIT over a panel of 400 kinases at a concentration of 1 μM except FLT3 and KDR (IC50s=91 and 130 nM, respectively).

Specifications

Chemical Name or Material PLX647
CAS 873786-09-5
Color Deep Yellow
Purity Grade Notes Research
Molecular Formula C21H17F3N4
Quantity 5 mg
Solubility Information DMSO : 25 mg/mL (65.38 mM; Need ultrasonic)
SMILES FC(C1=CC=C(CNC2=NC=C(CC3=CNC4=NC=CC=C43)C=C2)C=C1)(F)F
Molecular Weight (g/mol) 382.38
Formula Weight 382.38
Percent Purity 99.07%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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