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  5. Tocris Bioscience™ PNU 120596

Tocris Bioscience™ PNU 120596
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Product Code. 18756686
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25 mg
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18756686 5 mg 5mg
18736696 25 mg 25mg
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Product Code. 18756686 Supplier Tocris Bioscience™ Supplier No. 2498/5

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Description

Positive allosteric modulator of α7 nAChRs; active in vivo

PNU 120596 is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (EC50 = 216 nM), with no detectable effect on α4β2, α3β4 and α9α10 receptors. Active in vivo following systemic administration. Neuroprotective in an in vivo model of transient focal cerebral ischemia.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea
CAS 501925-31-1
Assay Percent Range >99%
Quantity 5 mg
Molecular Formula C13H14ClN3O4
Formula Weight Observed MW: 311.72
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