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Invitrogen™ POLR2K Polyclonal Antibody

Product Code. 15919264
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Quantity:
100 μL
Unit Size:
100µL
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15919264 100 μL 100µL
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Product Code. 15919264 Supplier Invitrogen™ Supplier No. PA566564

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DVQPPKQQPMI YICGECHTEN EIKSRDPIRC RECGYRIMYK KRTKRLV Highest antigen sequence identity to the following orthologs - mouse 100%, rat 100%.

RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.
TRUSTED_SUSTAINABILITY

Specifications

Antigen POLR2K
Applications Immunocytochemistry
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene POLR2K
Gene Accession No. P53803
Gene Alias ABC10-alpha; DNA directed RNA polymerases I, II, and III 7.0 kda polypeptide; DNA-directed RNA polymerase II subunit K; DNA-directed RNA polymerases I, II, and III subunit RPABC4; hRPB7.0; hsRPB10a; MafY; mCG145114-like; metallothionein-I gene transcription activator; Mt1a; POLR2K; polymerase (RNA) II (DNA directed) polypeptide K; polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa; polymerase (RNA) II subunit K; RNA polymerase II 7.0 kDa subunit; RNA polymerase II subunit K; RNA polymerases I, II, and III subunit ABC4; RPABC4; RPB10alpha; RPB12; RPB7.0
Gene Symbols POLR2K
Host Species Rabbit
Immunogen Recombinant Human POLR2K. Recombinant protein control fragment (Product #RP-107219).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5440
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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