missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 15921895

Invitrogen™ POT1 Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA575366

Product Code. 15921895

  • € 530.00 / 100µL

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

POT1 is a component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. It is a component of the double-stranded telomeric DNA-binding TRF1 complex which is involved in the regulation of telomere length by cis-inhibition of telomerase. Pot1 also acts as a single-stranded telomeric DNA-binding protein and thus may act as a downstream effector of the TRF1 complex and may transduce information about telomere maintenance and/or length to the telomere terminus. It binds to two or more telomeric single-stranded 5'-TTAGGG-3' repeats (G-strand) and with high specificity to a minimal telomeric single-stranded 5'-TAGGGTTAG-3' sequence. Its activity is TERT dependent but it does not increase TERT activity.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

POT1
Polyclonal
Unconjugated
POT1
1500031H18Rik; AI505244; AI851169; CMM10; DKFZp586D211; Dolichyl-phosphate-mannose--protein mannosyltransferase 1; GLM9; HPOT1; mPot1; Pomt1; POT 1; POT1; POT-1; Pot1a; POT1-like telomere end-binding protein; protection of telomeres 1; protection of telomeres 1 homolog; protection of telomeres 1A; protection of telomeres protein 1; protein O-mannosyltransferase 1; Protein O-mannosyl-transferase 1; protein-O-mannosyltransferase 1
Rabbit
Antigen affinity chromatography
RUO
101185, 25913, 500054
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
1 mg/mL
PBS with 0.02% sodium azide; pH 7.2
Q91WC1, Q9NUX5
POT1, Pot1a
Synthetic peptide corresponding to amino acids 269-315 of Human POT1.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Produktvorschläge

Produktvorschläge

Videos
Sicherheitsdatenblatt (SDS)
Dokumentation

Dokumentation

Produktzertifizierungen
Aktionen

Aktionen

Berichtigung von Produktinhalten

Bitte geben Sie uns Ihr Feedback zu den Produktinhalten, indem Sie das folgende Formular ausfüllen.

Name des Produkts

Indem Sie auf Absenden klicken, erklären Sie sich damit einverstanden, dass Fisher Scientific sich mit Ihnen in Verbindung setzen kann, um Ihr Feedback in diesem Formular zu bearbeiten. Wir werden Ihre Informationen nicht für andere Zwecke weitergeben. Alle bereitgestellten Kontaktinformationen werden in Übereinstimmung mit unserer Datenschutzrichtlinie aufbewahrt. Datenschutzrichtlinie.

Vielen Dank, dass Sie uns helfen, unsere Website zu verbessern. Ihr Feedback wurde übermittelt