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Invitrogen™ POU6F1 Polyclonal Antibody

Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Brn-5 (Brain-5), also known as POU6F1, MPOU or TCFB1, is a widely expressed protein but during embryogenesis is exclusively found in the developing brain and spinal cord. As is characteristic of Brn family members, Brn-5 contains two DNA-binding domains, namely the POU-specific domain and the POU homeodomain, which each contain an HTH (helix-turn-helix) motif. Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and is capable of both enhancing Prolactin gene expression and activating Pit-1 expression.
Specifications
Specifications
| Antigen | POU6F1 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | POU6F1 |
| Gene Accession No. | P56223, Q07916, Q14863 |
| Gene Alias | 2310038G18Rik; brain-5; Brain-specific homeobox/POU domain protein 5; BRN5; brn-5; brn-5 protein; C79593; cns-1; Emb; MPOU; mPOU homeobox protein; Octamer-binding transcription factor EMB; POU class 6 homeobox 1; POU domain, class 6, transcription factor 1; Pou6f1; TCFB1; transcription regulatory protein MCP-1 |
| Gene Symbols | POU6F1 |
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