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Invitrogen™ PPARGC1B Recombinant Rabbit Monoclonal Antibody (JM33-24)
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Product Code. 16356174
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
16356174 100 μL 100µL
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Product Code. 16356174 Supplier Invitrogen™ Supplier No. MA532765

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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
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Specifications

Antigen PPARGC1B
Applications Flow Cytometry, Immunoprecipitation, Western Blot
Classification Recombinant Monoclonal
Clone JM33-24
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Ppargc1b
Gene Accession No. Q811R2, Q86YN6
Gene Alias 4631412G21Rik; ERR ligand 1; ERRL1; Perc; peroxisome proliferative activated receptor gamma coactivator 1 beta; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1beta-2a; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; PGC1; pgc-1 beta; PGC-1(beta); Pgc1b; PGC1beta; PGC-1beta; PGC-1-beta; PGC-1beta/ERRL1; PGC-1-related estrogen receptor alpha coactivator; PPAR gamma coactivator-1beta protein; PPARG coactivator 1 beta; PPARgamma coactivator 1 beta; PPAR-gamma coactivator 1-beta; PPARGC1; PPARGC1B; PPARGC-1-beta
Gene Symbols Ppargc1b
Host Species Rabbit
Immunogen Synthetic peptide within Human PGC1 beta aa 974-1023.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 133522, 291567
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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