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Description
Immunogen sequence: PNIQKLLYQR FNTLAGGMEG TPFYQPSPSQ DFMGTLADVD NGNTNANGNL EELPPAQPTA PLPAEPAPSS DANDNELPSP EPEELICPQT THQTAEPAED NNNNVATVPT TEQIPSPVAE APSPGEEQVP PAPLPPASHP PATSTNK Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
This gene encodes a member of the ASPP family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
Specifications
Specifications
| Antigen | PPP1R13B |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | PPP1R13B |
| Gene Accession No. | Q62415, Q96KQ4 |
| Gene Alias | AI449786; Apoptosis-stimulating of p53 protein 1; apoptosis-stimulating protein of p53, 1; ASPP1; AW545810; KIAA0771; p53BP2-like; p85; Ppp1r13b; Protein phosphatase 1 regulatory subunit 13B; protein phosphatase 1, regulatory (inhibitor) subunit 13B; protein phosphatase 1, regulatory subunit 13B; Tp53bp2; transformation related protein 53 binding protein 2; Trp53bp2; tumor protein p53 binding protein, 2; tumor protein p53-binding protein, 2 |
| Gene Symbols | PPP1R13B |
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