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Invitrogen™ PPP1R9B Polyclonal Antibody

Product Code. 15568592
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Quantity:
100 μg
Unit Size:
100µg
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15568592 100 μg 100µg
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Product Code. 15568592 Supplier Invitrogen™ Supplier No. PA548102

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Description

Sheep Polyclonal Antibody

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Protein phosphatase 1 regulatory subunit 9B (PPP1R9B), also known as Neurabin II or spinophilin, is a gene located on chromosome 17q21.32 that encodes a regulatory protein predominantly expressed in the brain. PPP1R9B is involved in modulating the activity of protein phosphatase 1 (PP1), a crucial enzyme in cellular signaling pathways responsible for dephosphorylation of target proteins. Spinophilin functions by anchoring PP1 to specific subcellular locations, such as synaptic sites, thereby influencing synaptic plasticity, neurotransmission, and signal transduction. This protein is integral to the maintenance and modulation of excitatory synapses, playing a role in cognitive processes including learning and memory. Alterations in PPP1R9B expression or function have been associated with neuropsychiatric disorders and cancer, reflecting its importance in neuronal integrity and its potential role in tumorigenesis. Research into PPP1R9B continues to explore its therapeutic potential in neurological disorders and its utility in understanding phosphatase-related cellular processes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP1R9B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Ppp1r9b
Gene Accession No. O35274, Q96SB3
Gene Alias Neb2; neurabin 2; neurabin II; neurabin-2; Neurabin-II; neural tissue-specific F-actin-binding protein II; nuerabin 2; p130; PP1bp134; PPP1R6; PPP1R9; PPP1R9B; Protein phosphatase 1 regulatory subunit 9B; protein phosphatase 1, regulatory (inhibitor) subunit 9B; protein phosphatase 1, regulatory subunit 9B; protein phosphatase 1, regulatory subunit 9B, spinophilin; SPINO; Spinophilin; SPL; Spn
Gene Symbols Ppp1r9b
Host Species Sheep
Immunogen E. coli-derived recombinant human PPP1R9B Lys289-Asp412.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84686, 84687
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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