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Invitrogen™ PPP2R1B Polyclonal Antibody
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Product Code. 16578401
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Quantity:
100 μL
Unit Size:
100µL
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16578401 100 μL 100µL
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Product Code. 16578401 Supplier Invitrogen™ Supplier No. PA593159

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YAIREAATNN LMKLVQKFGT EWAQNTIVPK VLVMANDPNY LHRMTTLFCI NALSEACGQE ITTKQMLPIV LKMAGDQVAN VRFNVAKSLQ KIGPILDTNA LQGEVKPVLQ KLGQDEDMDV KYFAQEAISV VAQRLRKLEF PVKDSGEPSV PRADKNHFPR PTVPGEDMGK GPVYQLRGDT RDTLAQLGIA ELVHFSQSTD; Positive Samples: Jurkat.

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2A family comprises subfamily members PP2A alpha and PP2A beta. The PP2A catalytic subunit associates with a variety of regulatory subunits. Regulatory subunits include PP2A-A alpha and -A beta, PP2A-B alpha and -B beta, PP2A-C alpha and -C beta, and PP2A-B56 alpha and -B56 beta.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PPP2R1B
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.71 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Ppp2r1b
Gene Accession No. P30154, Q4QQT4, Q7TNP2
Gene Alias 2410091N08Rik; AI790395; PP2A A beta; PP2A -AR1 beta; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta; PP2A, subunit A, PR65-beta isoform; PP2A, subunit A, R1-beta isoform; PP2AA beta; PP2A-A beta; PP2A-Abeta; PP2A-APR65 beta; PPP2R1B; PR65B; protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform; protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform; protein phosphatase 2 regulatory subunit A, beta; protein phosphatase 2 scaffold subunit Abeta; protein phosphatase 2, regulatory subunit A, beta; protein phosphatase 2, structural/regulatory subunit A, beta; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform
Gene Symbols Ppp2r1b
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 468-667 of human PP2A-Abeta/PR65β/PP2A-Aβ/PR65β/PPP2R1B (NP_8590501).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315648, 5519, 73699
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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