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Invitrogen™ PPP2R4 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA529755
This item is not returnable.
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Description
Recommended positive controls: A549, HeLa, HepG2, HCT116. Predicted reactivity: Mouse (96%), Rat (95%), Rabbit (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Specifications
| PPP2R4 | |
| Polyclonal | |
| Unconjugated | |
| PTPA | |
| 2610042B21Rik; C77440; MGC2184; N28142; OTTHUMP00000022333; phosphotyrosyl phosphatase activator; PP2A; PP2A phosphatase activator; PP2A subunit B' isoform PR53; PP2A, subunit B', PR53 isoform; Ppp2r4; PR53; protein phosphatase 2 phosphatase activator; protein phosphatase 2 regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit 4; protein phosphatase 2A activator, regulatory subunit B; protein phosphatase 2A regulatory subunit 4; protein phosphatase 2A, regulatory subunit B (PR 53); protein phosphatase 2A, regulatory subunit B' (PR 53); PTPA; Serine/threonine-protein phosphatase 2A activator; serine/threonine-protein phosphatase 2A regulatory subunit 4; Serine/threonine-protein phosphatase 2A regulatory subunit B' | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5524 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 0.74 mg/mL | |
| 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7 | |
| Q15257 | |
| PTPA | |
| Recombinant protein encompassing a sequence within the center region of human PPP2R4. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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