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Invitrogen™ PRAK Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5143007
This item is not returnable.
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Description
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
MAPKAPK5 (PRAK) is activated in response to cellular stress and pro-inflammatory cytokines. Activity of this kinase is regulated by p38 alpha and p38 beta. The protein encoded by PRAK is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of PRAK encoding distinct isoforms have been reported.
Specifications
| PRAK | |
| Polyclonal | |
| Unconjugated | |
| MAPKAPK5 | |
| MAP kinase-activated protein kinase 5; MAPK-activated protein kinase 5; MAPKAP kinase 5; Mapkapk5; MAPKAP-K5; MAPKAPK-5; mitogen-activated protein kinase-activated protein kinase 5; MK5; MK-5; p38-regulated/activated protein kinase; PRAK | |
| Goat | |
| Ammonium sulfate precipitation | |
| RUO | |
| 17165, 8550 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| O54992, Q8IW41 | |
| MAPKAPK5 | |
| Peptide with sequence C-PQVLEAQRRHQKEKS. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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