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PRAS40 Monoclonal Antibody (73P21), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen AHO1031

Additional Details : Weight : 0.50000kg

Product Code. 10008252

  • € 463.00 / Each
Estimated Shipment: 18-06-2024
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Description

Description

The Akt signaling pathway contributes to the regulation of apoptosis after a variety of cell death signals. AKT1S1, also known as PRAS40, is a proline-rich substrate of the kinase AKT1 and is thought to play a role in neuroprotection mediated by nerve growth factor (NGF) after transient focal cerebral ischemia. AKT1S1 is also a substrate and potential regulator of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Treatment with the insulin-like growth factor-1 (IGF1) can induce the phosphorylation of AKT1S1 via the PI3K/AKT signaling pathway in PC12 cells.
Specifications

Specifications

PRAS40
Monoclonal
0.5 mg/mL
PBS with 1% BSA and 0.1% sodium azide
Q96B36
AKT1S1
Recombinant full length human PRAS40 expressed in E. coli.
100 μg
Primary
Human
Antibody
IgG1 κ
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
73P21
Unconjugated
AKT1S1
1110012J22Rik; 40 kDa proline-rich AKT substrate; AI227026; AKT1 substrate 1; AKT1 substrate 1 (proline rich); AKT1 substrate 1 (proline-rich); akt1s1; Lobe; Lobel; OTTHUMP00000196756; OTTHUMP00000196760; PKB/Akt substrate 40; Pras; PRAS40; Proline-rich AKT substrate; proline-rich AKT1 substrate 1
Mouse
purified
RUO
84335
-20°C
Liquid
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