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Invitrogen™ PRDM8 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA528414
This item is not returnable.
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Description
Recommended positive controls: HCT116. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival.
Specifications
| PRDM8 | |
| Polyclonal | |
| Unconjugated | |
| PRDM8 | |
| EPM10; PFM5; PR domain 8; PR domain zinc finger protein 8; PR domain-containing protein 8; PRDM8; PR-domain containing protein 8 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 56978 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 10% glycerol and 0.01% thimerosal; pH 7 | |
| Q9NQV8 | |
| PRDM8 | |
| Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human PRDM8. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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