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Invitrogen™ PREX1 Polyclonal Antibody

Description
Recommended positive controls: MCF-7, human PREX1-transfected 293T cells (partial). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Specifications
Specifications
| Antigen | PREX1 |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | PREX1 |
| Gene Accession No. | Q8TCU6 |
| Gene Alias | G630042G04; KIAA1415; OTTHUMP00000031228; Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; PIP3 dependent Rac exchange factor 1; PREX 1; PREX1; P-Rex1; PREX-1; ptdIns(3,4,5)-dependent Rac exchanger 1; RGD1306534; SET domain containing 6; Setd6 |
| Gene Symbols | PREX1 |
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