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Invitrogen™ PRMT9 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA548942

Product Code. 15683235

  • € 520.00 / 400µL

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Description

Description

PRMT9 Polyclonal Antibody for Western Blot

Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as DTL/CDT2, BCL6 and PRDM1/BLIMP1. The SCF(FBXO11) complex mediates ubiquitination and degradation of BCL6, thereby playing a role in the germinal center B-cells terminal differentiation toward memory B-cells and plasma cells. The SCF(FBXO11) complex also mediates ubiquitination and degradation of DTL, an important step for the regulation of TGF-beta signaling, cell migration and the timing of the cell-cycle progression and exit. Binds to and neddylates phosphorylated p53/TP53, inhibiting its transcriptional activity. SCF(FBXO11) does not seem to direct ubiquitination of p53/TP53.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PRMT9
Polyclonal
Unconjugated
PRMT9
AI931714; Prmt10; PRMT9; protein arginine methyltransferase 10 (putative); protein arginine methyltransferase 9; Protein arginine N-methyltransferase 10; Protein arginine N-methyltransferase 9; putative protein arginine N-methyltransferase 10; putative protein arginine N-methyltransferase 9; RGD1306157
Rabbit
Antigen affinity chromatography, Protein A
RUO
102182, 90826
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.4
Q3U3W5, Q6P2P2
PRMT9
KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human PRMT10.
400 μL
Primary
Human, Mouse
Antibody
IgG
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