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Progesterone R/NR3C3 Antibody (SPM566), Alexa Fluor™ 647, Novus Biologicals™

Product Code. 18151252 Shop All Bio Techne Products
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Product Code. 18151252 Supplier Novus Biologicals Supplier No. NBP234429AF647

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Description

Mouse Monoclonal Antibody

Progesterone R/NR3C3 Monoclonal specifically detects Progesterone R/NR3C3 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Progesterone R/NR3C3
Applications Western Blot, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone SPM566
Conjugate Alexa Fluor 647
Dilution Western Blot, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Gene Alias NR3C3PRNuclear receptor subfamily 3 group C member 3, progesterone receptor
Gene Symbols PGR
Host Species Mouse
Immunogen Recombinant full-length human Progesterone R/NR3C3 protein (PGR) (Uniprot: P06401 )
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Breast Cancer, Cancer
Primary or Secondary Primary
Gene ID (Entrez) 5241
Test Specificity This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues.
Target Species Human
Content And Storage Store at 4C in the dark.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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