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Invitrogen™ Prohibitin Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA527329
Description
Recommended positive controls: 293T, A431, HeLa, HepG2, NIH-3T3, PC-12. Predicted reactivity: Mouse (99%), Rat (99%), Zebrafish (93%), Xenopus laevis (92%), Dog (100%), Cat (100%), Chicken (95%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Prohibitin is from an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.
Specifications
| Prohibitin | |
| Polyclonal | |
| Unconjugated | |
| PHB | |
| BAP 32; Bap32; B-cell receptor-associated protein 32; epididymis luminal protein 215; epididymis secretory sperm binding protein Li 54e; fa18f07; fb09f05; HEL-215; HEL-S-54e; OTTHUMP00000165765; OTTHUMP00000165766; OTTHUMP00000220103; OTTHUMP00000220170; OTTHUMP00000220171; PHB; phb protein; PHB1; Prohibitin; sr:nyz128; wu:fa18f07; wu:fb09f05 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 18673, 25344, 5245 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry | |
| 0.34 mg/mL | |
| PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P35232, P67778, P67779 | |
| PHB | |
| Recombinant protein encompassing a sequence within the center region of human Prohibitin. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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