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Invitrogen™ PSMB4 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA527521
This item is not returnable.
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Description
Recommended positive controls: A431, H1299, HeLa. Predicted reactivity: Mouse (96%), Rat (94%), Xenopus laevis (81%), Pig (96%), Rabbit (96%), Rhesus Monkey (99%), Bovine (96%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit.
Specifications
| PSMB4 | |
| Polyclonal | |
| Unconjugated | |
| PSMB4 | |
| 26 kDa prosomal protein; HN3; HsBPROS26; HsN3; Lmp3; Low molecular mass protein 3; macropain beta chain; Multicatalytic endopeptidase complex beta chain; PROS26; PROS-26; Pros-27; proteasome (prosome, macropain) subunit, beta type 4; proteasome (prosome, macropain) subunit, beta type, 4; proteasome beta 4 subunit; proteasome beta chain; Proteasome chain 3; proteasome subunit beta 4; proteasome subunit beta type-4; proteasome subunit HsN3; proteasome subunit, beta type, 4; Psmb4; RN3; testis tissue sperm-binding protein Li 79P | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 5692 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.73 mg/mL | |
| 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 | |
| P28070 | |
| PSMB4 | |
| Recombinant protein encompassing a sequence within the center region of human Proteasome beta 4. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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