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Invitrogen™ PSMC3IP Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand: Invitrogen™ PA543070

Product Code. 15535862

€ 520.00 / 100µL

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Description

Peptide sequence: RLKNIKAATN HVTPEEKEQV YRERQKYCKE WRKRKRMATE LSDAILEGYP Sequence homology: Cow: 93%; Dog: 100%; Goat: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 86%; Rat: 93%.

PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

Specifications

Antigen	PSMC3IP
Classification	Polyclonal
Conjugate	Unconjugated
Gene	PSMC3IP
Gene Alias	C79099; DBD-interacting; Gt198; Homologous-pairing protein 2 homolog; homologous-pairing protein 2 homolog-like; Hop2; HUMGT198A; Nuclear receptor coactivator GT198; ODG3; proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein; proteasome 26S ATPase subunit 3-interacting protein; PSMC3 interacting protein; PSMC3-interacting protein; PSMC3IP; Tat-binding protein 1-interacting protein; TBP-1-interacting protein; Tbpip
Host Species	Rabbit
Purification Method	Protein A
Regulatory Status	RUO
Gene ID (Entrez)	29893
Content And Storage	-20°C, Avoid Freeze/Thaw Cycles
Form	Liquid

Applications	Western Blot
Concentration	1 mg/mL
Formulation	PBS with 2% sucrose and 0.09% sodium azide
Gene Accession No.	Q9P2W1
Gene Symbols	PSMC3IP
Immunogen	Synthetic peptide directed towards the middle region of human PSMC3IP.
Quantity	100 μL
Primary or Secondary	Primary
Target Species	Human
Product Type	Antibody
Isotype	IgG

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Invitrogen™ PSMC3IP Polyclonal Antibody

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