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Invitrogen™ PSMD8 Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552329

Product Code. 15740281

  • € 580.00 / 100µL

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Description

Description

Immunogen sequence: NRVAEFHTEL ERLPAKDIQT NVYIKHPVSL EQYLMEGSYN KVFLAKGNIP AESYTFFIDI LLDTIRDEIA GCIEKAYEKI LFTEATRILF FNTPKKMTDY AKKRGWVLGP NNYYSFASQQ QKPEDTTIPS TELAKQVIEY ARQ Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 97%.

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PSMD8
Polyclonal
Unconjugated
PSMD8
26S proteasome non-ATPase regulatory subunit 8; 26S proteasome regulatory subunit p31; 26S proteasome regulatory subunit RPN12; 26S proteasome regulatory subunit S14; 6720456J22Rik; AA407360; AL033291; AL033322; AL033323; C76433; epididymis secretory sperm binding protein Li 91n; HEL-S-91n; HIP6; HYPF; Nin1p; p31; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8; proteasome 26S non-ATPase subunit 8; proteasome 26S subunit, non-ATPase 8; proteasome 26S subunit, non-ATPase, 8; Psmd8; Rpn12; S14
Rabbit
Antigen affinity chromatography
RUO
292766, 5714, 57296
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.1 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P48556, Q9CX56
PSMD8
Recombinant protein corresponding to Human PSMD8. Recombinant protein control fragment (Product #RP-89240).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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