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PSMF1 Monoclonal Antibody (OTI2D7), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA505275
This item is not returnable.
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Description
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.Specifications
| PSMF1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| Q92530 | |
| PSMF1 | |
| Full length human recombit protein of human PSMF1 produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunocytochemistry, Immunofluorescence, Western Blot | |
| OTI2D7 | |
| Unconjugated | |
| PSMF1 | |
| PI31 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 9491 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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