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Invitrogen™ PSMF1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA583537
This item is not returnable.
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Description
Immunogen sequence: SSMILNVLEY GSQQVADLTL NLDDYIDAEH LGDFHRTYKN SEELRSRIVS GIITPIHEQW EKANVSSP Highest antigen sequence indentity to the following orthologs: Mouse - 82%, Rat - 82%.
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Specifications
| PSMF1 | |
| Polyclonal | |
| Unconjugated | |
| PSMF1 | |
| AW048666; BC012260; hPI31; PI31; proteasome (prosome, macropain) inhibitor subunit 1; proteasome (prosome, macropain) inhibitor subunit 1 (PI31); proteasome inhibitor PI31 subunit; proteasome inhibitor subunit 1; PSMB2; Psmf1; RP23 402M7.5; RP4 545L17.1; RP4-545L17.1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9491 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q92530 | |
| PSMF1 | |
| Recombinant protein corresponding to Human PSMF1. Recombinant protein control fragment (Product #RP-99413). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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