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Invitrogen™ PTCH Polyclonal Antibody
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Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142733

Product Code. 17857912

  • € 465.00 / 100µL

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Description

Description

Additional Information: This antibody is expected to recognize all reported isoforms (NP_000255.2; NP_001077072.1; NP_001077071.1; NP_001077073.1). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PTCH
Polyclonal
Unconjugated
Ptch1
A230106A15Rik; BCNS; etID309849.2; FLJ26746; FLJ42602; HGNC:9585; HPE7; lep; leprechaun; mes; mesenchymal dysplasia; NBCCS; OTTHUMP00000021709; OTTHUMP00000021710; patched; Patched 1; patched 2; patched homolog 1; patched homolog 2; patched protein; patched1; patched-2 protein; patched-like protein; protein patched homolog 1; Ptc; ptc1; ptc-1; ptc2; Ptch; PTCH protein +12b; PTCH protein +4'; PTCH protein -10; PTCH protein -3; PTCH protein -3,4,5; PTCH1; Ptch1 protein +12b; PTCH11; Ptch2; RP11-435O5.3
Goat
Ammonium sulfate precipitation
RUO
19206, 5727
-20°C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.5 mg/mL
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Q13635, Q61115
Ptch1
Peptide with sequence C-EELKKINYQVDSWEE.
100 μg
Primary
Human, Mouse
Antibody
IgG
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