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PTH Antibody (PTH/911), Alexa Fluor™ 594 - N-terminal, Novus Biologicals™

Mouse Monoclonal Antibody

Brand:  Novus Biologicals NBP2-54433AF594

Product Code. 18225173

  • € 521.00 / 0.10mL

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Description

Description

PTH Monoclonal specifically detects PTH in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PTH
Monoclonal
Alexa Fluor 594
50 mM sodium borate with 0.05% sodium azide
PTH
A synthetic peptide around amino acids 1-34 of human mature-PTH-polypeptide (exact sequence is proprietary) (Uniprot: P01270)
Primary
Epitope of this monoclonal antibody maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Store at 4°C in the dark.
Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
PTH/911
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Parathormone, Parathyrin, parathyroid hormone, parathyroid hormone 1, PTH1
Mouse
0.1 mL
5741
Human
IgG2b κ
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