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Invitrogen™ PTP1B Recombinant Rabbit Monoclonal Antibody (1G3)
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Product Code. 17267213 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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17267213 100 μL 100µL
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Product Code. 17267213 Supplier Invitrogen™ Supplier No. MA538341

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Description

Rabbit Recombinant Monoclonal Antibody

This antibody has been tested in direct-ELISA.

PTP1B (PTPN1) is a tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. It mediates dephosphorylation of EIF2AK3/PERK and in turn inactivates the protein kinase activity of EIF2AK3/PERK. PTP1B also plays a role in CKII- and p60c-src-induced signal transduction cascades. It regulates the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. PTP1B also regulates the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PTP1B
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone 1G3
Concentration 1.02 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 150mM NaCl and 0.02% sodium azide; pH 7.4
Gene PTPN1
Gene Accession No. P18031
Gene Alias CPTP1; EC 3.1.3.48; EGK_02300; hgnc9642; KIAA0283; protein tyrosine phosphatase 1B; protein tyrosine phosphatase non-receptor type 1; protein tyrosine phosphatase, non-receptor type 1; protein tyrosine phosphatase, placental; protein-protein-tyrosine phosphatase HA2; protein-tyrosine phosphatase 1B; Protein-tyrosine phosphatase HA2; PTN1; Ptp; PTP1B; PTP-1B; ptp1b protein; PTP-HA2; Ptpn1; RP5-1121H13.2; RPTPrho; tyrosine phosphatase 1b; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 1; wu:fk54h03
Gene Symbols PTPN1
Host Species Rabbit
Immunogen A synthesized peptide derived from human PTP1B.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5770
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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