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Invitrogen™ PTPRM Polyclonal Antibody
Goat Polyclonal Antibody
Brand: Invitrogen™ PA5142321
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Description
Additional Information: This antibody is expected to recognise both reported isoforms (NP_001098714.1 and NP_002836.3). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms.
Specifications
| PTPRM | |
| Polyclonal | |
| Unconjugated | |
| PTPRM | |
| hR-PTPu; Kiaa4044; MGC166994; mKIAA4044; protein tyrosine phosphatase mu; protein tyrosine phosphatase receptor type M; protein tyrosine phosphatase receptor-type M; protein tyrosine phosphatase, receptor type M; protein tyrosine phosphatase, receptor type, M; protein tyrosine phosphatase, receptor type, mu polypeptide; protein tyrosine phosphatase, receptor-type, M; protein-tyrosine phosphatase mu; PTP mu; Ptpmu; PTPRL1; PTPRM; receptor-type tyrosine-protein phosphatase mu; RPTPM; RPTPmu; R-PTP-MU; RPTPU | |
| Goat | |
| Ammonium Sulfate Precipitation | |
| RUO | |
| 5797 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P28827 | |
| PTPRM | |
| Peptide with sequence C-KLIRQVDKWQEEYN. | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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