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PTPRO Mouse anti-Human, CoraLite 488, Clone: 2F2B4, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech CL488-67000-100UL

Product Code. 17294716

  • € 450.00 / 100µL

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Description

Description

PTPRO(receptor-type tyrosine-protein phosphatase O) is also named as GLEPP1, PTPU2 and belongs to the protein-tyrosine phosphatase family. The protein is a receptor-like membrane protein tyrosine phosphatase expressed at the apical membrane of the podocyte foot processes in the kidney(PMID:21722858). The 1,159-amino acid predicted mature protein contains a large extracellular domain, a single transmembrane domain, and a single intracellular PTPase domain. Defects in PTPRO are the cause of nephrotic syndrome type 6 (NPHS6). In reducing conditions, PTPRO can form a smear from 180 to 220 kDa; In non-reducing conditions, a band appeares around 350 kDa, which likely represents the dimeric form of full-length PTPRO (PMID: 19573017).

Specifications

Specifications

PTPRO
Monoclonal
1000 μg/mL
Mouse
Primary
Human, Mouse, Rat
IgG2b
Immunofluorescence
2F2B4
CoraLite 488
100 μL
5800
Liquid
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