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Invitrogen™ PUF60 Monoclonal Antibody (GT3510)
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA527821
This item is not returnable.
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Description
Positive Control: mouse brain, rat brain, 293T, A431, HeLa, HepG2 Predicted Reactivity: Chicken (94%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
PUF60 encodes a protein that is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Specifications
| PUF60 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| Q3UEB3, Q9UHX1, Q9WV25 | |
| Puf60 | |
| Recombinant protein encompassing a sequence within the center region of human PUF60. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| GT3510 | |
| Unconjugated | |
| Puf60 | |
| 2410104I19Rik; 2810454F19Rik; 60 kDa poly(U)-binding-splicing factor; FBP interacting repressor; FBP-interacting repressor; FIR; FLJ31379; FUSE-binding protein-interacting repressor; LOW QUALITY PROTEIN: poly(U)-binding-splicing factor PUF60; poly(U) binding splicing factor 60; poly(U) binding splicing factor 60KDa; poly(U)-binding-splicing factor PUF60; poly-U binding splicing factor 60; poly-U binding splicing factor 60K; poly-U binding splicing factor 60KDa; PUF60; pyrimidine tract binding splicing factor; RNA-binding protein Siah-BP; Ro ribonucleoprotein-binding protein 1; Ro-binding protein 1; RoBP1; ROBPI; Siah binding protein 1; siah binding protein 1; FBP interacting repressor; pyrimidine tract binding splicing factor; Ro ribonucleoprotein-binding protein 1; siah-binding protein 1; SIAHBP1; Siah-BP1; similar to fuse-binding protein-interacting repressor isoform a; VRJS | |
| Mouse | |
| Protein G | |
| RUO | |
| 22827, 67959, 84401 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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