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Invitrogen™ PYY Monoclonal Antibody (4)
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Product Code. 15326301
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Quantity:
400 μL
Unit Size:
200µL
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15326301 400 μL 200µL
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Product Code. 15326301 Supplier Invitrogen™ Supplier No. ABS0510402

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Description

Mouse Monoclonal Antibody

Specificity: ABS 051-04-02 binds human PYY (3-36). This antibody does not cross-react with PYY (1-36) from mouse, rat, dog or pig samples. Reactivity: ABS 051-04-02 binds free PYY (3-36) in solution. The recommended ELISA dilution is 1:20,000 for PYY (3-36) coated directly at 1 μg/mL. ABS 051-04-02 can be used as a capture antibody in a sandwich ELISA using biotinylated detection antibody ABS 029-01-02. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL.

Peptide tyrosine-tyrosine amide (3-36), or PYY (3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY (3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY (3-36) is additive to that of the co-secreted gut hormone GLP-1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PYY
Applications ELISA, Western Blot
Classification Monoclonal
Clone 4
Concentration 1.06 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene Pyy
Gene Accession No. P10082
Gene Alias GHYY; Peptide tyrosine tyrosine; peptide tyrosine-tyrosine (YY); peptide YY; peptide YY (mapped); Peptide YY(3-36); Peptide YY3-36; Peptide YY3-37; peptide-YY; prepro-PYY; PYY; PYY II; PYY1; PYY-1; PYY-2; PYYI; PYY-I; PYYII; PYY-II; RATGHYY; Yy
Gene Symbols Pyy
Host Species Mouse
Immunogen Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.
Purification Method Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5697
Target Species Human
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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