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Invitrogen™ PZP Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA559582

Product Code. 15797431

  • € 560.00 / 100µL

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Description

Description

Immunogen sequence: VSSVYNLLTV KDLTNFPDNV DQQEEEQGHC PRPFFIHNGA IYVPLSSNEA DIYSFLKGMG L Highest antigen sequence identity to the following orthologs: Mouse - 51%, Rat - 48%.

The protein encoded by this gene is highly expressed in late-pregnancy serum and is similar in structure to alpha-2-macroglobulin. The encoded protein, which acts as a homotetramer, inhibits the activity of all four classes of proteinases. This protein contains cleavage sites for several proteinases. Upon binding of a proteinase, the conformation of this protein changes to trap the proteinase, limiting its activity. This protein appears to be elevated in the sera of presymptomatic Alzheimer's disease patients.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

PZP
Polyclonal
Unconjugated
PZP
A1m; A1m {ECO:0000312; A2m; AI893533; alpha 1 macroglobulin; alpha-1-M; Alpha-1-macroglobulin; alpha-1-macroglobulin 165 kDa subunit; Alpha-1-macroglobulin 45 kDa subunit; alpha-2-M; alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6; CPAMD6; EMBL:AAA40723.1}; MAM; Pregnancy zone protein; pregnancy-zone protein; Pzp; PZP, alpha-2-macroglobulin like
Rabbit
Antigen Affinity Chromatography
RUO
5858
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin)
0.4 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P20742
PZP
Recombinant protein corresponding to Human PZP. Recombinant protein control fragment (Product #RP-98418).
100 μL
Primary
Human
Antibody
IgG
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